Overview
On Site
USD 99,900.00 - 166,500.00 per year
Full Time
Skills
Research and development
Clinical trials
Process engineering
Data Analysis
Technology transfer
Health care
Recruiting
Chemicals
Analytical skill
Science
Design
Operations
SAFE
Chemistry
Art
Data
Management
Mentorship
Communication
Presentations
Leadership
Pharmaceutics
IMPACT
Patents
Publications
Coaching
Research
Payments
Legal
Law
Interviewing
Immigration
Job Details
Principal Scientist, Chemical Process and Analytical Development
Why Patients Need You
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Process Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
What You Will Achieve
The Chemical Process and Analytical Development (CPAD) department at Pfizer is seeking a Principal Scientist to discover and develop robust and innovative synthetic routes to novel Drug-Linkers to drive the next generation of targeted cancer therapy. As a Principal Scientist, you will be at the center of our operations and find that everything we do is in line with an unwavering commitment to quality. You will drive the development of safe and scalable chemistry by leveraging state-of-the-art technologies such as continuous processing, high-throughput experimentation, data-rich experimentation, catalysis, and predictive technologies. You will spearhead the advancement of Pfizer's portfolio through personal laboratory effort as well as overseeing internal and external resources. You will serve as a technical and strategic leader for early and late-phase programs while mentoring junior staff members and promoting a supportive and inclusive work environment. You may directly supervise staff and drive the development of those employees. You will propose technical and strategic solutions to Sr. management and represent process chemistry in cross-functional teams requiring excellent communication skills. You will establish an external presence as technical leader in the field by authoring journal articles and presenting at leading external scientific meetings.
Key Responsibilities
This is a laboratory based role requiring light lifting and manual laboratory work 4-8 hours per day.
Non-Standard Work Schedule, Travel or Environment Requirements
This is a salaried role that can, but infrequently requires nights or weekend to achieve a timeline.
Relocation support available
Work Location Assignment: On Premise
The annual base salary for this position ranges from $99,900.00 to $166,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Research and Development
Why Patients Need You
Pfizer's purpose is to deliver breakthroughs that change patients' lives. Process Research and Development is at the heart of fulfilling Pfizer's purpose as we work to translate advanced science and technologies into the therapies that matter most. Whether you are in the discovery sciences, ensuring drug safety and efficacy or supporting clinical trials, you will apply cutting edge design and process development capabilities to accelerate and bring the best-in-class medicines to patients around the world.
What You Will Achieve
The Chemical Process and Analytical Development (CPAD) department at Pfizer is seeking a Principal Scientist to discover and develop robust and innovative synthetic routes to novel Drug-Linkers to drive the next generation of targeted cancer therapy. As a Principal Scientist, you will be at the center of our operations and find that everything we do is in line with an unwavering commitment to quality. You will drive the development of safe and scalable chemistry by leveraging state-of-the-art technologies such as continuous processing, high-throughput experimentation, data-rich experimentation, catalysis, and predictive technologies. You will spearhead the advancement of Pfizer's portfolio through personal laboratory effort as well as overseeing internal and external resources. You will serve as a technical and strategic leader for early and late-phase programs while mentoring junior staff members and promoting a supportive and inclusive work environment. You may directly supervise staff and drive the development of those employees. You will propose technical and strategic solutions to Sr. management and represent process chemistry in cross-functional teams requiring excellent communication skills. You will establish an external presence as technical leader in the field by authoring journal articles and presenting at leading external scientific meetings.
Key Responsibilities
- Design and execute well-planned laboratory experiments that require complex data analysis
- Be recognized as a technical leader internally and externally by d emonstrating advanced intellectual and technical abilities
- Employ state-of-the art technologies, including flow chemistry, high-throughput experimentation, catalysis, data-rich experimentation, computational tools, and predictive tools
- Be familiar with early and late phase pharmaceutical development and regulatory expectations
- Contribute directly to technology transfer to internal sites or external vendors
- Leverage knowledge and experience to guide cross-functional teams on impact of decisions
- Effectively manage CRO/CMO resources
- Maintain high standards for all laboratory records, reports, patents, and external communications
- Establish and deliver on tight timelines aligned with our portfolio goals
- Build strong relationships with stakeholders to advocate for our department and group members
- Communicate difficult concepts, ideas, problems, and solutions persuasively to project teams, leadership, and cross-functional teams
- Author publications, patents, regulatory submissions and present externally
- Provide career development coaching, mentoring, and feedback to junior staff and direct reports
- Promote a supportive and inclusive work environment
- Maintain an understanding of the activities and research executed by the group members
- Experience in targeted therapeutics industry is a plus
- PhD in Organic Chemistry with 5+ years of industrial experience or a Master's degree and 14+ years of experience
- This is an on-site designated role, and you will work five days per week on-site
This is a laboratory based role requiring light lifting and manual laboratory work 4-8 hours per day.
Non-Standard Work Schedule, Travel or Environment Requirements
This is a salaried role that can, but infrequently requires nights or weekend to achieve a timeline.
Relocation support available
Work Location Assignment: On Premise
The annual base salary for this position ranges from $99,900.00 to $166,500.00. In addition, this position is eligible for participation in Pfizer's Global Performance Plan with a bonus target of 15.0% of the base salary and eligibility to participate in our share based long term incentive program. We offer comprehensive and generous benefits and programs to help our colleagues lead healthy lives and to support each of life's moments. Benefits offered include a 401(k) plan with Pfizer Matching Contributions and an additional Pfizer Retirement Savings Contribution, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage. Learn more at Pfizer Candidate Site - U.S. Benefits | (uscandidates.mypfizerbenefits.com). Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.
Relocation assistance may be available based on business needs and/or eligibility.
Sunshine Act
Pfizer reports payments and other transfers of value to health care providers as required by federal and state transparency laws and implementing regulations. These laws and regulations require Pfizer to provide government agencies with information such as a health care provider's name, address and the type of payments or other value received, generally for public disclosure. Subject to further legal review and statutory or regulatory clarification, which Pfizer intends to pursue, reimbursement of recruiting expenses for licensed physicians may constitute a reportable transfer of value under the federal transparency law commonly known as the Sunshine Act. Therefore, if you are a licensed physician who incurs recruiting expenses as a result of interviewing with Pfizer that we pay or reimburse, your name, address and the amount of payments made currently will be reported to the government. If you have questions regarding this matter, please do not hesitate to contact your Talent Acquisition representative.
EEO & Employment Eligibility
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as work authorization and employment eligibility verification requirements of the Immigration and Nationality Act and IRCA. Pfizer is an E-Verify employer. This position requires permanent work authorization in the United States.
Research and Development