Principal Software & Cloud Architect Registry Informatics

Job Title: Principal Software & Cloud Architect Registry Informatics

Location : Bay Area CA

Hybrid (with periodic travel to key offices and client sites)

About the Role

We re seeking a hands-on Principal Architect to lead the modernization of our Registry Informatics platform. You ll own the end-to-end technical strategy to transform a monolithic, EAV-based application into a scalable, secure, and cost-efficient microservices platform tailored for cancer registry workflows, data quality, and long-term cloud efficiency.

You ll collaborate cross-functionally to translate architectural assessments into a multi-year modernization roadmap and drive its execution.

Key Responsibilities

1. Application Architecture & Modernization

• Assess current monolithic application (UI, services, data access); document modules, dependencies, hotspots

• Define target microservices architecture aligned with:

  • Cancer registry workflows (abstracting, casefinding, QA, reporting)

  • Interoperability standards (HL7, NAACCR, state/national reporting)

• Apply strangler pattern for incremental modernization:

  • Prioritize domains (e.g., import/export, reporting, casefinding, user management)

  • Define service boundaries, APIs, and data contracts

• Create architecture blueprints, reference implementations, and guardrails

2. Data Architecture EAV Optimization & Normalization

• Analyze existing EAV schema

• Propose hybrid data model:

  • Normalized schemas for stable entities

  • Flexible EAV/JSON structures for variable data

• Lead schema evolution and migration strategy

• Collaborate with DBAs to improve indexing, partitioning, and query plans

• Introduce abstraction layers or ORM patterns

3. Query Performance & Observability

• Profile and optimize high-latency queries

• Establish performance SLOs and baseline metrics (e.g., p95 latency)

• Implement:

  • Query optimization, caching, materialized views

  • Observability stack (tracing, metrics, logs)

• Partner with Support and SRE/Ops to reduce performance-related cases

4. Cloud Architecture & Cost Optimization

• Review current cloud deployment and cost drivers

• Design scalable cloud architecture:

  • Containerization (Kubernetes or equivalent)

  • Autoscaling for app/DB tiers

  • Tiered storage strategies

• Implement cost governance:

  • Tagging, dashboards, anomaly alerts

  • Long-term optimization (reserved capacity, storage tiering, compute rightsizing)

• Collaborate with finance/product/engineering on 3 5 year cost trajectory

5. Migration Factory Legacy New Registry Informatics

• Build repeatable migration framework:

  • Data profiling, mapping, validation, reconciliation

  • Automation for parallel migrations

• Architect processes to minimize downtime and manual errors

• Collaborate with customer-facing teams for scalable, predictable migrations

6. DevOps, Security, and Compliance

• Define standards for:

  • CI/CD pipelines, build/release automation

  • API design, versioning, backward compatibility

• Ensure compliance with HIPAA, data residency, audit trails

• Design for tenant isolation, data protection, and auditability

7. Technical Leadership & Collaboration

• Act as technical lead and advisor to engineering, product, and executives

• Mentor engineers on architecture, microservices, and data design

• Communicate trade-offs to technical and non-technical stakeholders

• Translate roadmap into actionable epics, stories, and milestones

Qualifications

Must-Have

• 10+ years in software engineering/architecture; 5+ years as lead/principal architect

• Proven experience modernizing monolithic applications to microservices

• Strong data modeling and relational DB design (including EAV schemas)

• Hands-on query performance tuning and DB optimization

• Deep cloud architecture expertise (Azure, AWS, or Google Cloud Platform):

  • Containerization, orchestration, scaling, storage, monitoring

• Experience in regulated domains (healthcare, life sciences, financial services)

• Systems thinking and roadmap execution skills

• Excellent communication across technical and executive audiences

Nice-to-Have

• Experience in oncology, cancer registry, or healthcare informatics

• Familiarity with NAACCR standards or public health data standards

• Experience with multi-tenant SaaS platforms

• Background in DevOps/SRE and observability

• Prior work with migration factories or high-volume data migrations

Reporting & Collaboration

• Reports to: Head of Engineering / VP of Product & Technology

• Collaborates with:

  • Product Management (registry, reporting, interoperability)

  • Engineering Managers and Tech Leads

  • Cloud/DevOps, DBAs, SRE/Ops

  • Support and Migration Teams

  • Security, Compliance, and Finance