Cell Line Development Research Associate

Software Guidance & Assistance, Inc., (SGA), is searching for a Cell Line Development Research Associate for a contract assignment with one of our premier Pharmaceutical clients in South San Francisco, CA.

Responsibilities:

• Involved in the creation of stable cell lines for the recombinant adeno-associated viral vector (rAAV) production processes .
• Executes experiments, produces relevant documentation, and works under supervision.
• Culturing mammalian cells for viral production in shake flasks, spinner flasks, spin tubes, deep well and automation platforms.
• Performing experiments in the development, optimization and scale-up of AAV producer cell lines.
• Preparing process development protocols, data analysis summaries, technical reports, and other relevant process documentation.
• Optimization of transfection and transduction protocols for newly engineered cell lines.
• Maintaining an accurate laboratory notebook.
• Ensuring work conforms to applicable quality and safety standards.
• Participating on project teams (as needed).

Required Skills:

• B.S. with 3-6 years of experience, MS.c with 2-5 years of relevant scientific or technical experience in the life sciences industry or equivalent
• Experience in cell culture including materials, instruments and technologies is essential.
• Hands-on experience in mammalian cell culture production processes is a critical requirement. This includes small scale (shaker flasks, spinner flasks, spin tubes, deep well) and/or benchtop bioreactor scale.
• Effective communication skills (verbal, written, interpersonal).
• Must be able to interact with cross-functional teams.
• Analytical and problem-solving skills.
• Ability to manage time effectively.
• Teamwork is a must.
• Must be able to lift 25 pounds.
• Due to the inherent nature of cell culture, some weekend work and/or work on holidays may be needed. On occasion, long work hours may be required depending upon the experiment schedule.
• Handling large volumes of cell culture or related materials, such as tens of liters, may be required. Also, several viral materials, including AAV may be involved in the work.

Preferred Skills:

• Experience with viral vector production is preferred .
• Industry experience is a plus but not required
• Basic Knowledge on AAV biology is a plus.
• Experience in laboratory automation hardware and software is a plus.
• Experience with creation, analysis and characterization of new engineered cell lines and stability studies (subcloning, clonal expansion, transient transfection and expression screening) is a strong plus.
• Experience in molecular biology techniques (plasmid design, molecular cloning, SDS-PAGE/western blotting, qPCR, etc) is a strong plus.
• Automation and ELN experience is a strong plus.

SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it. You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion at work. Please find us at .

SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our services, programs, and activities. Please visit our company to request an accommodation or assistance regarding our policy
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