Principal Engineer Jobs in North Carolina

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Principal Process Engineer

Katalyst Healthcares and Lifesciences

Wilson, North Carolina, USA

Full-time

Job Description: We are seeking a Principal Process Engineer with a strong background in GMP manufacturing and engineering. The ideal candidate will have hands-on experience in biologics, process systems, automation, and utilities with a focus on upstream and/or downstream processes. The role will be initially remote and then onsite in Wilson , NC, once the facility opens. Responsibilities: Provide technical leadership in GMP large molecule biologics manufacturing. Engineer and modify proce

Principal Applications Integration Engineer - Shockwave

Johnson & Johnson

Remote or Santa Clara, California, USA

Full-time

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn m

Senior Principal Systems Safety Engineer (Hybrid)

RTX Corporation

Remote or Cedar Rapids, Iowa, USA

Full-time

Date Posted: 2025-05-12 Country: United States of America Location: HIA32: Cedar Rapids, IA 400 Collins Rd NE , Cedar Rapids, IA, 52498-0505 USA Position Role Type: Hybrid U.S. Citizen, U.S. Person, or Immigration Status Requirements: The ability to obtain and maintain a U.S. government issued security clearance is required.Security Clearance: DoD Clearance: Secret Collins Aerospace is seeking an experienced System Safety Engineer within our Missions Systems organization. This engineer will b

Principal Software Engineer, Generative AI

Autodesk Inc.

Colorado, USA

Full-time

Job Requisition ID # 25WD86528 Position Overview Autodesk is leading the transformation of the AEC industry, integrating AI technology into our products. We're enhancing our applications with cloud-native capabilities, including data at scale, edge computing, AI-based solutions, and advanced 3D modeling and graphics. This innovation is happening across our flagship products-AutoCAD, Revit, Construction Cloud-and Forma, our new Industry Cloud. As a Principal Full-Stack Software Developer on th

Principal Software Engineer - ITSI

Splunk Inc.

Remote or San Jose, California, USA

Full-time

Description Splunk, a Cisco company, is building a safer and more resilient digital world with an end-to-end full stack platform made for a hybrid, multi-cloud world. Leading enterprises use our unified security and observability platform to keep their digital systems secure and reliable. Our customers love our technology, but it's our caring employees that make Splunk stand out as an amazing career destination. No matter where in the world or what level of the organization, we approach our wor

(USA) Principal, Data Engineer

Walmart Inc.

Remote or Bentonville, Arkansas, USA

Full-time

Position Summary What you'll do Come join our People Data Engineering Team @Walmart where you'll have the opportunity to manage people data at Walmart scale and make sure the consistent data is being utilized across transactional and analytical systems. About Team: The Enterprise People Technology team supports the successful deployment and adoption of new People technology across the enterprise. As a Fortune #1 company, our work impacts millions of associates globally. We strive to continuou

Principal Software Engineer - Remote

First-Citizens Bank & Trust Company

Remote or Phoenix, Arizona, USA

Full-time

Overview This is a remote role that may only be hired in the following location(s): AZ or CA This position provides expert technical guidance on large, complex, and strategic projects with significant impact. Facilitates the creation and implementation of software systems and software development. Consults and provides subject matter expertise on software evaluations, feasibility studies, and new technologies. Specializes in software development and integration with third party solutions, as a

Principal Software Engineer - Remote

First-Citizens Bank & Trust Company

Remote or California, USA

Full-time

Overview This is a remote role that may only be hired in the following location(s): AZ or CA This position provides expert technical guidance on large, complex, and strategic projects with significant impact. Facilitates the creation and implementation of software systems and software development. Consults and provides subject matter expertise on software evaluations, feasibility studies, and new technologies. Specializes in software development and integration with third party solutions, as a

Principal Software Engineer - Remote

First-Citizens Bank & Trust Company

Remote or Phoenix, Arizona, USA

Full-time

Overview This is a remote role that may only be hired in the following location(s): AZ or CA This position provides expert technical guidance on large, complex, and strategic projects with significant impact. Facilitates the creation and implementation of software systems and software development. Consults and provides subject matter expertise on software evaluations, feasibility studies, and new technologies. Specializes in software development and integration with third party solutions, as a

Principal Software Engineer, Observability (Backend)

Splunk Inc.

California, USA

Full-time

Description Splunk, a Cisco company, is building a safer and more resilient digital world with an end-to-end full stack platform made for a hybrid, multi-cloud world. Leading enterprises use our unified security and observability platform to keep their digital systems secure and reliable. Our customers love our technology, but it's our caring employees that make Splunk stand out as an amazing career destination. No matter where in the world or what level of the organization, we approach our wor

Principal Software Engineer, Virtual Economy Optimization

Roblox

Remote or San Mateo, California, USA

Full-time

Every day, tens of millions of people come to Roblox to explore, create, play, learn, and connect with friends in 3D immersive digital experiences- all created by our global community of developers and creators. At Roblox, we're building the tools and platform that empower our community to bring any experience that they can imagine to life. Our vision is to reimagine the way people come together, from anywhere in the world, and on any device.We're on a mission to connect a billion people with op

Senior Principal Machine Learning Engineer-AI (FULLY REMOTE)

Splunk Inc.

Remote or San Jose, California, USA

Full-time

Description Join us as we pursue our disruptive new vision to make machine data accessible, usable and valuable to everyone. We are a company filled with people who are passionate about our product and seek to deliver the best experience for our customers. At Splunk, we're committed to our work, customers, having fun and most importantly to each other's success. Learn more about Splunk careers and how you can become a part of our journey! Role: As the Senior Principal Machine Learning Enginee

Principal Software Development Engineer

CVS Health

Remote or Monroeville, Pennsylvania, USA

Full-time

At CVS Health, we're building a world of health around every consumer and surrounding ourselves with dedicated colleagues who are passionate about transforming health care. As the nation's leading health solutions company, we reach millions of Americans through our local presence, digital channels and more than 300,000 purpose-driven colleagues - caring for people where, when and how they choose in a way that is uniquely more connected, more convenient and more compassionate. And we do it all w

MacOS EndPoint Software Engineer C++ Swift

Request Technology, LLC

Remote

Full-time

We are unable to sponsor for this permanent full-time role Position is bonus eligible Prestigious Enterprise Security Services Company is currently seeking a MacOS EndPoint Software Engineer with C++ and Swift, and preferably Rust experience. Candidate will develop macOS-specific Security Extensions, using Network Extensions and the Endpoint Security Framework. Responsibilities: Design Agent Functionality for macOS: Handle packaging, installation, secure updates, and system integration for endpo

Principal Mechanical Engineer

Westinghouse Electric Company LLC

North Carolina, USA

Full-time

Principal Mechanical Engineer Westinghouse Electric Company Cranberry Twp., PA Are you interested in being part of an innovative team that supports Westinghouse's mission to provide clean energy solutions? At Westinghouse, we recognize that our employees are our most valuable asset and we seek to identify, attract and recruit the most qualified talent while recognizing and encouraging the value of diversity in the global workplace. About the role: As a Principal Mechanical Engineer, you wil

Principal Systems Engineer - Reliability & Maintainability Engineer

Sierra Nevada Corporation

Remote or Lone Tree, Colorado, USA

Full-time

If you like solving complex engineering problems using your analytical skills, this is the opportunity for you! As a Reliability and Maintainability Engineer, you will perform detailed analysis to establish reliability predictions, monitor equipment data for continuous validation of reliability predictions, and author reports summarizing your analysis. As a cross-functional engineer, you are in charge of system-level ownership of new products and processes through the product life cycle. This in

Principal Network Engineer

Commonspirit Health

Remote or Englewood, Colorado, USA

Full-time

Overview Inspired by faith. Driven by innovation. Powered by humankindness. CommonSpirit Health is building a healthier future for all through its integrated health services. As one of the nation's largest nonprofit Catholic healthcare organizations, CommonSpirit Health delivers more than 20 million patient encounters annually through more than 2,300 clinics, care sites and 137 hospital-based locations, in addition to its home-based services and virtual care offerings. CommonSpirit has more tha

Principal Fluid Systems Engineer

Westinghouse Electric Company LLC

North Carolina, USA

Full-time

Principal Fluid Systems Engineer Westinghouse Electric Company Cranberry Twp, PA Are you interested in being part of an innovative team that supports Westinghouse's mission to provide clean energy solutions? At Westinghouse, we recognize that our employees are our most valuable asset and we seek to identify, attract and recruit the most qualified talent while recognizing and encouraging the value of diversity in the global workplace. About the role: As a Principal Fluid Systems Engineer, you w

EndPoint Security Staff Engineer Rust C++

Request Technology, LLC

Remote

Full-time

We are unable to sponsor for this permanent full-time role Position is bonus eligible Prestigious Enterprise Security Services Company is currently seeking a EndPoint Security Staff Engineer with Rust and C++ experience. Candidate will help lead the design and development of our cross-platform endpoint agent. This role is instrumental in shaping both the technical architecture and future direction of our Windows, Linux, and macOS protection capabilities. Responsibilities: Own the technical visio

Principal level IT Infrastructure Engineer / Re-IP

Prudent Technologies and Consulting

Remote

Contract

Network/Systems Lead Engineer Network Integration (Re-IP) Fully REMOTE contract , but weekly travel required. Travel can be anywhere in the US; however it will primarily be in the northeast. So, the preference is someone located in the northeast US like Massachusetts Re-IP Acceleration Technical Lead Principal level IT Infrastructure Engineer with broad and deep infrastructure knowledge and experience across network, server, and end-user device technologies. Accountable for 1) providing techni