Principal Software Engineer Jobs in Missouri

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Staff Software Engineer, AI Solutions

10x Genomics

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California, USA

Full-time

About the role 10x Genomics helps researchers answer biology's hardest and most elusive questions with single cell and spatial biology technology. We're harnessing the power of AI and large language models (LLMs) to revolutionize how researchers interact with their data and drive discovery. As an AI/LLM Engineer, you'll be at the forefront of developing intelligent, user-centric solutions that assist scientists and internal teams throughout their research journey-from experimental design and d
Posted 7 days ago | Updated 9 hours ago

Comcast Cybersecurity: Principal Engineer, Advanced Threat Response

Comcast Corp

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Remote or Philadelphia, Pennsylvania, USA

Full-time

Make your mark at Comcast -- a Fortune 30 global media and technology company. From the connectivity and platforms we provide, to the content and experiences we create, we reach hundreds of millions of customers, viewers, and guests worldwide. Become part of our award-winning technology team that turns big ideas into cutting-edge products, platforms, and solutions that our customers love. We create space to innovate, and we recognize, reward, and invest in your ideas, while ensuring you can prou
Posted 33 days ago | Updated 9 hours ago

Lead Software Engineer

Parsons Services Company

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Remote or Colorado Springs, Colorado, USA

Full-time

In a world of possibilities, pursue one with endless opportunities. Imagine Next! When it comes to what you want in your career, if you can imagine it, you can do it at Parsons. Imagine a career working with exceptional people sharing a common quest. Imagine a workplace where you can be yourself. Where you can thrive. Where you can find your next, right now. We've got what you're looking for. Job Description: Parsons is seeking an amazingly talented Software Engineer Lead to join our growing
Posted 56 days ago | Updated 9 hours ago

Principal, Development Engineer - Hybrid in Pittsburgh

Constellation Energy

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Remote or Warrendale, Pennsylvania, USA

Full-time

WHO WE ARE As the nation's largest producer of clean, carbon-free energy, Constellation is focused on our purpose: accelerating the transition to a carbon-free future. We have been the leader in clean energy production for more than a decade, and we are cultivating a workplace where our employees can grow, thrive, and contribute. Our culture and employee experience make it clear: We are powered by passion and purpose. Together, we're creating healthier communities and a cleaner planet, and our
Posted 12 days ago | Updated 9 hours ago

Senior Staff Software Engineer - Fullstack

ServiceNow, Inc.

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Remote or Addison, Texas, USA

Full-time

Company Description It all started in sunny San Diego, California in 2004 when a visionary engineer, Fred Luddy, saw the potential to transform how we work. Fast forward to today - ServiceNow stands as a global market leader, bringing innovative AI-enhanced technology to over 8,100 customers, including 85% of the Fortune 500 . Our intelligent cloud-based platform seamlessly connects people, systems, and processes to empower organizations to find smarter, faster, and better ways to work. But thi
Posted 1 day ago | Updated 9 hours ago

Senior Staff Software Engineer - Fullstack

ServiceNow, Inc.

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Remote or San Diego, California, USA

Full-time

Company Description It all started in sunny San Diego, California in 2004 when a visionary engineer, Fred Luddy, saw the potential to transform how we work. Fast forward to today - ServiceNow stands as a global market leader, bringing innovative AI-enhanced technology to over 8,100 customers, including 85% of the Fortune 500 . Our intelligent cloud-based platform seamlessly connects people, systems, and processes to empower organizations to find smarter, faster, and better ways to work. But thi
Posted 1 day ago | Updated 9 hours ago

Principal Engineer

NVIDIA Corporation

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California, USA

Full-time

We are now looking for a Principal Research Engineer focused on Generative AI inference. Are you excited to change the way people infuse AI into products and services? NVIDIA is at the forefront of generative AI models, from language to images. NVIDIA's provides building blocks to democratize AI and make generative AI easy to develop, integrate, and deploy. Our team is dedicated to developing optimized inferencing technologies to support our growing generative AI needs. We contribute to all step
Posted 60+ days ago | Updated 9 hours ago

Lead Software Engineer - Remote

UnitedHealth Group

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Remote or Eden Prairie, Minnesota, USA

Full-time

Optum is a global organization that delivers care, aided by technology to help millions of people live healthier lives. The work you do with our team will directly improve health outcomes by connecting people with the care, pharmacy benefits, data and resources they need to feel their best. Here, you will find a culture guided by inclusion, talented peers, comprehensive benefits and career development opportunities. Come make an impact on the communities we serve as you help us advance health op
Posted 12 days ago | Updated 9 hours ago

Lead Software Engineer - Supply Chain Replenishment

Publix

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Remote or Lakeland, Florida, USA

Full-time

Publix Super Markets, Inc. is the largest privately-owned food retailer in the nation with more than 1,200 stores and more than 200,000 associates throughout the Southeast. We are associate-owned, proud of our family atmosphere, and consistently named as one of the best companies to work for in America. We are largely debt-free and renowned for our financial performance as well as our premier customer service. Publix?s Information Services (I/S) department is located in Lakeland, Florida and Alp
Posted 24 days ago | Updated 2 hours ago

Staff Software Engineer, Developer Infra (Python)

Airbnb

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Remote

Full-time

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: Dev Infra's mission is to enable Airbnb developers to develop, merge and release high quality code quickly a
Posted 31 days ago | Updated 9 hours ago

Principal System Security Engineer

Draper

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Remote or Cambridge, Massachusetts, USA

Full-time

Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas
Posted 60+ days ago | Updated 9 hours ago

(USA) Staff, Software Engineer

Walmart Inc.

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Remote or Bellevue, Washington, USA

Full-time

Position Summary What you'll do Join our innovative and dynamic People Technology engineering team as a Staff Software Engineer. In this role, you'll play a crucial part in designing, developing, and implementing digital solutions that address mission-critical business challenges, supporting Walmart associates. Your projects will make a significant impact, be scalable, and drive Walmarts modernization efforts in the People Technology organization. About Team: The Enterprise People Technology
Posted 28 days ago | Updated 9 hours ago

Lead Software Engineer (Remote)

First-Citizens Bank & Trust Company

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Remote or Georgia, USA

Full-time

Overview This is a remote role that may only be hired in the following location(s): AZ, GA, NC and TX We are looking for a hands-on Lead Software Engineer who provides technology solutions and integration services in following areas: Payments & Money movement, information reporting. The ideal candidate should have the necessary skills and experience to provide technical guidance, estimation of efforts, understanding and deciding upon the optimal technology solution to achieve the desired busin
Posted 20 days ago | Updated 6 hours ago

Staff Software Engineer, Onchain DevX

Coinbase

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Remote

Full-time

Ready to be pushed beyond what you think you're capable of? At Coinbase, our mission is to increase economic freedom in the world. It's a massive, ambitious opportunity that demands the best of us, every day, as we build the emerging onchain platform - and with it, the future global financial system. To achieve our mission, we're seeking a very specific candidate. We want someone who is passionate about our mission and who believes in the power of crypto and blockchain technology to update the
Posted 14 days ago | Updated 9 hours ago

Staff Software Engineer, Compute Data Plane

Airbnb

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Remote

Full-time

Airbnb was born in 2007 when two hosts welcomed three guests to their San Francisco home, and has since grown to over 5 million hosts who have welcomed over 2 billion guest arrivals in almost every country across the globe. Every day, hosts offer unique stays and experiences that make it possible for guests to connect with communities in a more authentic way. The Community You Will Join: The Cloud Infrastructure team is responsible for delivering and operating the foundational platforms and clo
Posted 6 days ago | Updated 9 hours ago

Principal Product Engineer - HOKA Footwear

Deckers Brands

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Remote or Portland, Oregon, USA

Full-time

At Deckers Brands, Together, Every Step is a promise kept that every employee can bring their authentic self, is valued and supported, as a whole person, at work and beyond. Together, Every Step is how we continue to deliver exceptional business results, experience an amazing place to work, and have a positive impact on the communities and world around us. Job Title: Principal Product Engineer- HOKA Footwear Reports to: Director, Product Engineering Location: Portland, OR (Hybrid) The Role
Posted 53 days ago | Updated 9 hours ago

Lead Software Engineer

Salas O'Brien Engineers Incorporated

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Remote

Full-time

Lead Software Engineer - Job Description At Salas O'Brien we tell our clients that we're engineered for impact. This passion for making a difference applies just as much to our team as it does to our projects. That's why we're committed to living our values every day: inspiring, achieving, and connecting as shared owners of our success with a focus on a sustainable future. Building for the long-term means that all our team members can expect to work on amazing projects with a people-first appr
Posted 40 days ago | Updated 9 hours ago

Principal Space & Strategic Navigation Engineer

Draper

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Remote or Cambridge, Massachusetts, USA

Full-time

Overview: Draper is an independent, nonprofit research and development company headquartered in Cambridge, MA. The 2,000+ employees of Draper tackle important national challenges with a promise of delivering successful and usable solutions. From military defense and space exploration to biomedical engineering, lives often depend on the solutions we provide. Our multidisciplinary teams of engineers and scientists work in a collaborative environment that inspires the cross-fertilization of ideas
Posted 60+ days ago | Updated 9 hours ago

Principal Electrical Component Engineer (hybrid)

RTX Corporation

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Remote or Windsor, Connecticut, USA

Full-time

Date Posted: 2025-06-17 Country: United States of America Location: 01: Building 01 Windsor Locks One Hamilton Road, Windsor Locks, CT, 06096 USA Position Role Type: Hybrid U.S. Citizen, U.S. Person, or Immigration Status Requirements: Security Clearance: None/Not Required Joining Collins Aerospace isn't just about finding a job; it's about embarking on a journey to redefine the future of aerospace technology. Collins Aerospace, an RTX company, is a leader in technologically advanced and int
Posted 4 days ago | Updated 9 hours ago

(USA) Staff, Software Engineer

Walmart Inc.

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Remote or Bentonville, Arkansas, USA

Full-time

Position Summary What you'll do Who We Are Walmart is a multinational, people-led, tech-powered omnichannel retailer with over 2.2 million associates. At People.AI, we support and empower Walmart's People function with AI and GenAI solutions to enhance productivity, seize growth opportunities, prioritize well-being, and foster a culture of belonging for Walmart associates in both the U.S. and international markets. People.AI is a full-stack Generative AI team dedicated to delivering personali
Posted 57 days ago | Updated 9 hours ago