At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work-but it's work worth doing. If you're driven by purpose and ready to bring your best to work that truly matters for patients, we invite you to join us.
Job Position Overview:As a System Engineer, you will serve as a front-line technical support resource across the Tech at Lilly systems landscape, with primary focus on business systems, infrastructure and system configuration support, and support for QC Lab systems. You will partner with process automation, manufacturing operations, quality, and global Tech at Lilly teams to gather requirements, document business processes, and support the configuration, operation, troubleshooting, and continuous improvement of digital solutions, ensuring systems and processes maintain compliance with GMP requirements and data integrity principles throughout their lifecycle.
Responsibilities:- Provide day-to-day technical support and troubleshooting for business systems and related plant-floor interfaces, resolving incidents within service levels and escalating complex issues as needed.
- Develop a high-level understanding of the system and technology platform underlying assigned systems and become familiar with configuring and operating at least one aspect or subsystem, growing toward independent operation with decreasing supervision.
- Provide a supporting role in infrastructure activities (e.g., servers, network connectivity, user access, basic system configuration) needed to keep digital solutions running reliably.
- Provide technical support for QC Lab systems and instrument/software interfaces, coordinating with lab and quality personnel to resolve issues and maintain uptime.
- Gather and document business and functional requirements from manufacturing, quality, and IT stakeholders, and translate them into clear technical specifications and system requirements.
- Author, revise, and maintain SOPs, work instructions, and other process documentation, ensuring alignment with GMP requirements and validation practices.
- Support the design, configuration, qualification, and change management of systems, maintaining accurate project and validation documentation.
- Deliver prescribed tasks that help improve or maintain business solutions, applying and growing a basic knowledge of the business processes enabled by the system.
- Analyze systems and processes to identify opportunities for standardization, automation, and continuous improvement across the IT landscape.
- Build and maintain operational dashboards and reports (e.g., PowerBI) to provide visibility into plant, system, and process performance.
- Assist in developing training materials and support end-user adoption of new or updated digital solutions.
- Adhere to security, safety, and compliance protocols, including training requirements, SOPs, and policies related to system management.
Basic Requirements:- Bachelor's degree in computer science, IT, Engineering or related field
- 3+ years of relevant work experience in systems engineering, technical support, infrastructure, business/technical analysis, or a related discipline (internship experience considered).
- 2+ years experience working in GMP, pharmaceutical manufacturing.
- Qualified applicants must be authorized to work in the United States on a full-time basis. Lilly will not provide support for or sponsor work authorization or visas for this role, including but not limited to F-1 CPT, F-1 OPT, F-1 STEM OPT, J-1, H-1B, TN, O-1, E-3, H-1B1, or L-1.
Additional Skills/Preferences:- Actively learns and applies systems engineering technology, techniques, and tools; able to independently apply them with increasingly limited coaching and supervision.
- Has, or is developing, a high-level understanding of the system and technology platform underlying at least one aspect or subsystem, with a growing ability to configure and operate it.
- Basic understanding of GMP (Good Manufacturing Practice) requirements and regulated manufacturing environments.
- Familiarity with data integrity principles and practices.
- Previous experience with Manufacturing Execution Systems (MES) or manufacturing automation systems (e.g., DeltaV or similar platforms) is a plus.
- Exposure to data engineering and integration concepts, such as APIs, ETL processes, data historians, or databases.
- Basic understanding of IT infrastructure and system configuration, including servers, networking, and access management.
- Familiarity with QC Lab systems, instrumentation, or laboratory software interfaces is a plus.
- Proficient in translating business requirements into technical documentation and SOPs.
- Prior exposure to Computer System Validation (CSV) processes.
- Proven ability to analyze and resolve process- or system-related issues.
- Experience with Agile methodologies and tools (e.g., Scrum, Jira).
- Proficient in PowerBI or other data visualization and reporting tools.
- Strong analytical, problem-solving, and communication skills.
- Demonstrated learning agility and curiosity in a fast-paced technical environment.
Additional Information:- Position Location: Lebanon, Indiana, with potential travel to other U.S. and global Lilly sites as required.
- Travel Percentage (%): <10
- Shift Information: Role is Monday through Friday and based on-site. Must be flexible in providing support to accommodate other inputs (production schedules, shutdowns, etc.). Occasional extended hours and/or off-hour support may be required (includes the occasional weekend).
Lilly is dedicated to helping individuals with disabilities to actively engage in the workforce, ensuring equal opportunities when vying for positions. If you require accommodation to submit a resume for a position at Lilly, please complete the accommodation request form ( for further assistance. Please note this is for individuals to request an accommodation as part of the application process and any other correspondence will not receive a response.
Lilly is proud to be an EEO Employer and does not discriminate on the basis of age, race, color, religion, gender identity, sex, gender expression, sexual orientation, genetic information, ancestry, national origin, protected veteran status, disability, or any other legally protected status.
Our employee resource groups (ERGs) offer strong support networks for their members and are open to all employees. Our current groups include: Africa, Middle East, Central Asia (AMECA), Black Employees at Lilly (BE@Lilly), Chinese Culture Network (CCN), EnAble, Evolve, Lilly Indian Network (LIN), Organization of Latinx at Lilly (OLA), Pride (LGBTQ+ Allies), Veterans Leadership Network (VLN) and Women's Initiative for Leading at Lilly (WILL).
Actual compensation will depend on a candidate's education, experience, skills, and geographic location. The anticipated wage for this position is
$66,000 - $158,400
Full-time equivalent employees also will be eligible for a company bonus (depending, in part, on company and individual performance). In addition, Lilly offers a comprehensive benefit program to eligible employees, including eligibility to participate in a company-sponsored 401(k); pension; vacation benefits; eligibility for medical, dental, vision and prescription drug benefits; flexible benefits (e.g., healthcare and/or dependent day care flexible spending accounts); life insurance and death benefits; certain time off and leave of absence benefits; and well-being benefits (e.g., employee assistance program, fitness benefits, and employee clubs and activities).Lilly reserves the right to amend, modify, or terminate its compensation and benefit programs in its sole discretion and Lilly's compensation practices and guidelines will apply regarding the details of any promotion or transfer of Lilly employees.
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