Senior Python Developer Jobs in St. Louis, MO

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FullStackEngineer(AWS and Python)

Precision Technologies Corp

Remote

Full-time, Third Party

Here is the job opportunity information; Role: Full Stack Engineer(AWS and Python) Location: Remote Duration: Long Term Contract / Permanent Experience: 13+ Years MUST Mandatory Skills : React, node.js, AWS Lambda, API Gateway, Cloud watch, Python, Dynamo, must have hands on coding, Ci/cd, Terraform. We are looking for a talented and driven Full Stack Engineer with top proficiency in React, Node.js, and serverless technologies (specifically AWS Lambda) to join our dynamic engineering team. Profi

Healthcare Python/ ReactJS Engineer *Remote

Indus River Technologies Inc.

Remote

Contract

HEALTHCARE FULLSTACK - PYTHON/REACT JS12 month initial contract Targeting Rate -55/w2 Work Authorization: GC Remote - working EST HoursClient: GRC/CVS Key techs: Python, ReactJs, Google Cloud Platform, Rest API, FHIR or other healthcare systems Our client is seeking a Full Stack Python/ ReactJS Software Engineer. This resource will support healthcare data initiatives including an application modernization and AI chatbot integration. Key Responsibilities:Develop and enhance modern front-end f

Python Lead (Entry Level Architect with Hands-on coding) || 13+ years experience || remote position || LinkedIn must

Nestortechnologies Inc

Remote

Contract, Third Party

Python Lead (Entry Level Architect with Hands-on coding) 13+ years experience Remote position LinkedIn must Responsibilities: Design and implement data pipelines using Python, SQL, and Unix to ensure data quality and integrity.Work with Docker to containerize data pipelines and ensure scalability and portability.Collaborate with cross-functional teams to gather requirements and integrate data analytics into business operations.Ensure data privacy and security by implementing appropriate contr

GenAI Engineer ? LLM Fine-Tuning | Python | AWS

Mastech Digital

Remote or Dallas, Texas, USA

Contract

Mastech Digital provides digital and mainstream technology staff as well as Digital Transformation Services for all American Corporations. We are currently seeking a GenAI Engineer ? LLM Fine-Tuning | Python | AWS for our client in the Consulting domain. We value our professionals, providing comprehensive benefits and the opportunity for growth. This is a Contract position, and the client is looking for someone to start immediately. Duration: 12 Months Contract Location: Remote ? Dallas, TX 7503

Direct Client:: W2 Contract-Fulltime position:: Need Generative AI Architect with Fullstack Development, Python, LLMOps & Healthcare Expeirence:: 100% remote

Synergy Technologies, LLC

Remote

Contract

W2 contract to Fulltime position No Sponsorship required = Job Title: IT - Applications Development - Generative AI Architect Location: Jacksonville, FL (100% Remote) Job Description: As a Generative AI Architect, you will play a key role in designing, developing, and deploying AI-powered applications. You will work closely with cross-functional teams to build scalable, efficient, and innovative solutions that integrate seamlessly into our technology stack. Your expertise in model fine-tuning, r

Remote :: Python Lead/Architect (with hands-on coding)

IT First Source

Remote

Contract

Python Lead (Entry level Architect with Hands-on coding) || REMOTE ROLE Responsibilities: Design and implement data pipelines using Python, SQL, and Unix to ensure data quality and integrity.Work with Docker to containerize data pipelines and ensure scalability and portability.Collaborate with cross-functional teams to gather requirements and integrate data analytics into business operations.Ensure data privacy and security by implementing appropriate controls and protocolsStay up-to-date with e

Technical Operations Analyst with Python Work From Home - M

Next Step Systems

Remote

Full-time

Technical Operations Analyst with Python Work From Home We are currently looking for a Technical Operations Analyst for a great opportunity. The company participates in a wide variety of marketplaces including global futures, equities, commodities, options, fixed income, and cryptocurrencies. Their culture emphasizes teamwork and focuses on continuous integration and test-driven development. This position is 100% Remote. Technical Operations Analyst Responsibilities: - Oversee the operation a

Technical Operations Analyst with Python, Electronic Trading Systems Preferred Work From Home - M

Next Step Systems

Remote

Full-time

Technical Operations Analyst with Python, Electronic Trading Systems Preferred Work From Home We are currently looking for a Technical Operations Analyst for a great opportunity. The company participates in a wide variety of marketplaces including global futures, equities, commodities, options, fixed income, and cryptocurrencies. Their culture emphasizes teamwork and focuses on continuous integration and test-driven development. This position is 100% Remote. Technical Operations Analyst Respo

(Python Based) Lead Research Engineer

Thomson Reuters U.S. Inc.

Remote or Eagan, Minnesota, USA

Full-time

Lead Research Engineer Do you love creating innovative solutions for customers? We are seeking a passionate Lead Research Engineer who will bring expertise in AI and ML and is interested in building data-driven capabilities that drive transformation. As a member of Thomson Reuters Labs you will have a direct impact on our company by helping to create new and innovative capabilities that will delight our customers. What does Thomson Reuters Labs do? We experiment, we build, we deliver. We suppor

Python Backend Engineer

ACL Digital

Remote or San Jose, California, USA

Full-time

Job Title: Python Backend Engineer - Systems & Integration Location: Remote bout We are building a next-generation virtual assistant platform that enables natural and responsive voice and chat-based interactions. The platform integrates with internal and external systems to deliver seamless, real-time user experiences at scale. s part of our growing team, we're looking for a skilled Python Backend Engineer to help us build reliable, high-performance backend systems. Role Overview: This role inv

SDET - Python

Unify Technologies, Inc.

Remote

Full-time

Required Skills and Experience: Selenium, Python - Strong in coding Qualification: Master's/Bachelor's degree or equivalent in Computer Science related fields. Experience: 4+ years

Lead Engineer - Machine Learning / ML Ops (Python, PySpark, Vertex AI)

Target Corporation

Remote or Brooklyn Park, Minnesota, USA

Full-time

The pay range is $128,000.00 - $231,000.00 Pay is based on several factors which vary based on position. These include labor markets and in some instances may include education, work experience and certifications. In addition to your pay, Target cares about and invests in you as a team member, so that you can take care of yourself and your family. Target offers eligible team members and their dependents comprehensive health benefits and programs, which may include medical, vision, dental, life

Python Quality Engineer

ACL Digital

Remote or San Jose, California, USA

Full-time

Role: Python Quality Engineer Location: Remote About Us We are building a cutting-edge voice and chat platform for natural, responsive user interaction. Our systems operate at scale, with strong integration and performance demands. We're looking for a Python QA Engineer to ensure the platform's reliability, scalability, and user experience. Role Overview: As a Python Quality Engineer, you'll develop and maintain test automation frameworks, create simulation tools for testing, and drive quality t

Software Engineer II (Python or C#/.Net) Remote

ConsultNet, LLC

Remote or Birmingham, Alabama, USA

Full-time

Software Engineer II (Python or C#/.Net) Remote (EST or CST) 8 month contract Pay Rate: $50.00 to $52.00 per hr. We're looking for a hands-on Software Engineer II to support a major migration from a legacy system to a modern enterprise data platform. This role is part of an ongoing transformation project that began in early 2025. You'll help accelerate development by contributing to backend services and high-performance data pipelines in a collaborative Agile environment. Key Responsibilitie

Software Engineering Manager - CUDA Python

NVIDIA Corporation

Remote or Santa Clara, California, USA

Full-time

NVIDIA's invention of the GPU in 1999 sparked the growth of the PC gaming market, redefined modern computer graphics, and revolutionized parallel computing. More recently, GPU deep learning ignited modern AI - the next era of computing - with the GPU acting as the brain of computers, robots, and self-driving cars that can perceive and understand the world. We're looking to grow our company, and form teams with the most inquisitive people in the world. Join us at the forefront of technological ad

Software Engineer II - InsuraMatch (OpenAI, Javascript, Python, SQL)

Travelers

Remote or Hartford, Connecticut, USA

Full-time

Who Are We? Taking care of our customers, our communities and each other. That's the Travelers Promise. By honoring this commitment, we have maintained our reputation as one of the best property casualty insurers in the industry for over 160 years. Join us to discover a culture that is rooted in innovation and thrives on collaboration. Imagine loving what you do and where you do it. Compensation Overview The annual base salary range provided for this position is a nationwide market range and re

Software Development Engineer in Test II (Python & Networking) - Remote

Akamai Technologies

Cambridge, England, United Kingdom

Full-time

Would you like to impact the digital experiences of millions of users? Do you enjoy solving large scale distributed systems problems? Join our Edge Apps Engineering team! Our team tests all Products and Technologies across the Edge Apps Engineering group. We develop automation infrastructure for product testing and collaborate with the rest of the Engineering teams to qualify features. We are knowledgeable about all Delivery products and focus on System integration testing replicating real wo

Python Software Engineer, Data (Healthcare with Apache Airflow)

Genzeon

Remote

Contract, Third Party

About Genzeon Delivering excellence in IT services and solutions for the retail and healthcare sectors. Genzeon is a leading provider of intelligent automation, security, compliance, cloud, and managed services. Our healthcare capabilities integrate data systems, facilitate information flow, and leverage interoperability to improve clinical and operational outcomes. Genzeon empowers retail enterprises with multichannel IT solutions that deliver a personalized experience for consumers. Genzeon ha

Python Full Stack

Clover Solutions LLC

Remote

Full-time

Role: Python Full Stack Engineer Location: Remote Duration: Long Term Contract / Permanent Rate: $120K + Benefits - 13+ Years MUST Mandatory Skills : React, node.js, AWS Lambda, API Gateway, Cloud watch, Python, Dynamo, Must have hands on coding, Ci/cd, Terraform, We are looking for a talented and driven Full Stack Engineer with top proficiency in React, Node.js, and serverless technologies (specifically AWS Lambda) to join our dynamic engineering team. Proficient in Python, dynamo, cloudwatch,

Automation Engineer (Python/Ansible)

World Wide Technology

Remote

Contract

Automation Engineer (Python/Ansible) Company Overview World Wide Technology (WWT) is a global technology integrator and supply chain solutions provider. Through our culture of innovation, we inspire, build, and deliver business results, from idea to outcome. Based in St. Louis, WWT works closely with industry leaders such as Cisco, HPE, Dell EMC, NetApp, VMware, Intel, AWS, Microsoft, and F5, focusing on three market segments: Fortune 500 companies, service providers and the public sector. WWT i