Scientific Researcher- Lipid Nanoparticles (LNPs)

Software Guidance & Assistance, Inc., (SGA), is searching for a Scientific Researcher- L ipid Nanoparticles (LNPs) for a contract assignment with one of our premier Pharmaceutical Services clients in South San Francisco, CA.

Responsibilities :
The firm is seeking an outstanding Scientific Researcher to support formulation screening efforts within the Synthetic Molecule Pharmaceutical Sciences group. The successful candidate will contribute to the development and optimization of lipid nanoparticles (LNPs) and other parenteral formulations through high-throughput screening strategies and advanced analytical characterization. This role requires hands-on laboratory expertise, strong analytical skills, and the ability to work collaboratively within cross-functional teams to support pharmaceutical formulation development.

• Design and execute high-throughput formulation screening experiments for lipid nanoparticles (LNPs) and other parenteral drug delivery systems, using both bench instruments and automation tools.
• Physicochemical characterization of LNPs including particle size distribution, encapsulation efficiency, zeta potential, stability testing, etc.
• Solubility and stability screenings, solid state/polymorph characterizations to support formulation research and development.
• Design, plan, and troubleshoot laboratory experiments while maintaining strong attention to data quality and reproducibility.
• Analyze and interpret experimental data, generating clear reports, presentations, and summaries for project teams.
• Document experimental procedures and results in electronic laboratory notebooks (ELN) and internal data management systems.
• Collaborate with analytical scientists, formulation scientists, and cross-functional project teams to support development programs.
• Identify technical challenges and propose potential solutions to improve formulation performance and experimental workflows.
• Maintain compliance with laboratory safety standards, internal quality requirements, and regulatory guidelines.

Required Skills:

• BS or MS degree in Chemistry, Pharmaceutical Sciences, Chemical Engineering, or a related scientific discipline.
• 1 - 5 years of industrial experience in pharmaceutical formulation research and development.
• Strong theoretical knowledge of pharmaceutics; analytical, physical, and/or organic chemistry.
• Hands-on experience with LNP formulation and analytics, including microfluidics, dialysis and ultrafiltration, particle sizing, encapsulation efficiency analysis.
• Self-motivated with strong problem-solving capabilities to design and execute experiments independently.
• Excellent written and verbal communication skills to work effectively in a collaborative team environment.
• Pharmaceutical formulation development
• LNP and parenteral formulations
• High-throughput experimentation
• Analytical chemistry techniques
• Data analysis and interpretation
• Laboratory automation technologies
• Scientific problem solving
• Cross-functional collaboration

Preferred Skills:

• Hands-on experience with analytical tools including UV/Vis/fluorescence spectroscopy, HPLC-UV/CAD/MS, capillary electrophoresis, or related technologies.
• Experience in analyzing peptides and nucleic acids.
• Experience with lab automation and hands-on experience with robotic liquid and solid handlers.
• Experience performing high-content data analysis, AI/ML, and interpreting complex experimental results.

SGA is a technology and resource solutions provider driven to stand out. We are a women-owned business. Our mission: to solve big IT problems with a more personal, boutique approach. Each year, we match consultants like you to more than 1,000 engagements. When we say let's work better together, we mean it. You'll join a diverse team built on these core values: customer service, employee development, and quality and integrity in everything we do. Be yourself, love what you do and find your passion at work. Please find us at .

SGA is an Equal Opportunity Employer and does not discriminate on the basis of Race, Color, Sex, Sexual Orientation, Gender Identity, Religion, National Origin, Disability, Veteran Status, Age, Marital Status, Pregnancy, Genetic Information, or Other Legally Protected Status. We are committed to providing access, equal opportunity, and reasonable accommodation for individuals with disabilities in employment, and our services, programs, and activities. Please visit our company to request an accommodation or assistance regarding our policy.

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