Scientist

ApTask Global Workforce (AGW) is seeking a Scientist with a technology company. This is a 12+ month contract opportunity with our client located in South San Francisco, CA. This is an onsite position.

Summary:

The ideal candidate is a recent PhD graduate in Biochemistry, Chemical Biology, Molecular Biology, or a related field, with strong quantitative and analytical skills and a demonstrated ability to quickly learn and adapt in a laboratory environment. This role is best suited for an early-career scientist (0-2 years of postdoctoral or industry experience) with a solid foundation in scientific reasoning and data analysis. The hiring team is seeking a highly adaptable and trainable individual to be developed in-house on specific assay development techniques, particularly within cellular target engagement workflows.

Notes: General schedule: 8am - 5pm some flex

Responsibilities:

• Develop and optimize bioassays to ensure successful implementation and routine execution, supporting high-throughput screening (HTS), hit characterization, lead optimization, and mechanism-of-action (MOA) studies
• Design and conduct laboratory experiments, generate and interpret data to facilitate the development of assays and evaluate therapeutic agents
• Learn, apply, and integrate automation solutions during assay development, MOA studies, data analysis, and reporting processes
• Design, optimize, and implement workflows for cell line generation to enable the development of cell-based assays for screening and/or lead optimization
• Plan and execute experiments semi-independently and adapt readily to evolving project needs
• Identify, evaluate, and implement new methods and techniques to develop robust bioassays, generating reliable and reproducible data efficiently
• Stay current with the latest scientific literature and actively contribute to the interpretation of results

Requirements:

• Doctorate degree in Biochemistry, Chemical Biology, Molecular Biology, or a related field is mandatory
• Strong skills in quantitative biology
• Excellent analytical reasoning capabilities
• High adaptability in a laboratory environment
• Ability to follow established protocols to perform routine experiments, planning and adjusting procedures as needed
• Proficient with standard lab equipment and major techniques

Desired skills:

• Experience in collaborative work within a multi-disciplinary team in a biopharmaceutical environment
• Strong scientific foundation in understanding and implementing various bioassays and readouts, including TR-FRET, BRET, Alpha, MSD, HCS, luminescence, and fluorescence
• Expertise in the development and implementation of target engagement (TE), activity, functional, phenotypic, and protein-protein interaction (PPI) assays
• Extensive experience in the functional and phenotypic characterization of engineered cells with analytical techniques, including DNA sequencing, RT-qPCR, and Western Blots
• Experience in a variety of bioassays on more physiologically relevant cellular models such as iPSCs, 3D-culture, co-culture, and primary cells
• Competence in setting up and operating multimode plate readers and automated liquid handlers for the development of 384- and/or 1536-well microtiter plate assays
• Familiarity with software and statistical platforms necessary for analyzing large data sets, including Screener and Spotfire

Pay range: Up to $46.69 per Hour

Only candidates available and ready to work directly as ApTask Global Workforce (AGW) employees will be considered for this position.

If you have the described qualifications and are interested in this exciting opportunity, please apply!

ApTask Global Workforce (AGW)

ApTask Global Workforce (AGW) is a certified Minority and Veteran workforce solutions company. AGW delivers operational, clinical, lab and professional talent with a strong focus on healthcare and life sciences. The company supports clients with reliable staffing, program expertise and a commitment to quality, speed and consistent delivery.

Benefits of working with ApTask Global Workforce include:

• Medical
• Dental
• Vision
• Sick Pay (for applicable states/municipalities)

Our team stays close to the process and is here to guide you every step of the way. To learn more, please visit our website

ApTask Global Workforce is an Equal Opportunity Employer. Candidates will receive consideration without regard to their race, color, religion, sex, sexual orientation, gender identity, national origin, disability or status as a protected veteran.