Scientist I

Title - Scientist I
Location: San Diego, CA (Poseida). Onsite Role
Interview: 1x panel with HM & team.


Position Summary:
Client is searching for an outstanding Scientist I to join the Gene Therapy team in San Diego, CA.
This position offers an exciting opportunity to work with new non-viral nucleic acid delivery tools for in vivo and ex vivo genome editing and gene therapy applications. This person will be engaged in the analysis of Client nanoparticle-based pharmaceuticals.
Responsibilities may include but are not limited to:
Work at the direction of Analytical scientists to quantitate lipid nanoparticles (LNPs) encapsulating nucleic acids
Analyze raw materials for LNP formulations
Establish relationships between physiochemical characteristics of experimental nanoparticle formulations and their efficacy and safety
Maintain detailed records of analytical data
Interface directly with other functional teams
Share responsibility for basic lab management activities (supply ordering, instrument calibration, maintaining schedules)

Requirements, Knowledge, Skills, and Abilities:
Master''s or Bachelor''s degree with 2+ years'' experience in pharmaceutical sciences, bioengineering, chemical engineering, chemistry, or related scientific discipline (an equivalent combination of education and experience may be considered).
Practical experience using analytical methods such as RiboGreen, Dynamic Light Scattering (DLS), and Zeta potential measurement is strongly preferred
Prior experience with High-Performance Liquid Chromatography (HPLC) is preferred
Experience and proficiency with other analytical techniques will be considered
Proficiency at formulating buffers is required
Excellent attention to detail and ability to produce consistent results and effectively communicate them to the team
Ability to be a team player, multitask and work on multiple projects at once, and excel in a collaborative work environment.
Proficiency at MS Excel is required; prior experience with advanced analytical software (Prism, JMP) is desirable
Excellent oral and written communication skills