Role Overview We are seeking a Bioinformatics Test Engineer to validate and ensure the quality of NGS data pipelines and bioinformatics workflows. The role requires a strong blend of bioinformatics knowledge, QA expertise, and automation skills. Key Responsibilities • Design and execute testing strategies for NGS pipelines (alignment, variant calling, annotation) • Perform data validation, regression testing, and discrepancy analysis • Develop automated test scripts (Python) • Translate requirements into test cases and validation criteria • Work with CI/CD pipelines and cloud-based workflows • Collaborate with cross-functional teams to ensure data accuracy and reliability Required Skills • Strong understanding of NGS workflows (FASTQ, BAM, VCF) • Experience in bioinformatics pipeline testing or QA • Proficiency in Python scripting • Hands-on with Git and CI/CD tools • Experience with cloud platforms (AWS/Google Cloud Platform/Azure) and data pipelines • Strong problem-solving and communication skills Preferred • Experience in biotech/life sciences domain • Familiarity with Nextflow, Snakemake, or similar workflows • Exposure to regulated environments (CLIA/FDA) What We’re Looking For • Strong testing mindset + hands-on engineering skills • Ability to debug pipelines and explain thought process clearly • Experience with real-world data workflows (not just academic projects) • Mentions NGS pipelines + testing together • Has Python + Git + CI/CD • Mentions variant calling / VCF validation • Worked on cloud or production pipelines Reject or deprioritize if: • Only academic bioinformatics (no testing/QA) • Only statistics validation (no system testing) • No Python or automation • No infra experience (cloud / CI/CD / DB) • Only local scripts, no real pipelines Other High Priority Keywords Variant Calling Pipeline Testing Regression Testing Test Strategy OR Test Case Design Data Validation Golden Dataset OR Reference Dataset CI/CD OR "GitHub Actions" OR GitLab OR "Azure DevOps" AWS OR S3 OR Cloud Nextflow OR Snakemake OR WDL OR Cromwell Automation Testing
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