At Gilead, we're creating a healthier world for all people. For more than 35 years, we've tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer - working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world's biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.
Every member of Gilead's team plays a critical role in the discovery and development of life-changing scientific innovations. Our employees are our greatest asset as we work to achieve our bold ambitions, and we're looking for the next wave of passionate and ambitious people ready to make a direct impact.
We believe every employee deserves a great leader. People Leaders are the cornerstone to the employee experience at Gilead and Kite. As a people leader now or in the future, you are the key driver in evolving our culture and creating an environment where every employee feels included, developed and empowered to fulfil their aspirations. Join Gilead and help create possible, together.
Job DescriptionWe are seeking a Senior Architect, Intelligent Solutions who thrives in a hybrid role that blends technical leadership with hands-on delivery. In this role, you will serve as the technical lead for contractor engineering teams, own delivery outcomes for your function within cross-functional initiatives, and remain deeply engaged in the work itself, contributing to architecture, solution design, and complex problem-solving.
You will oversee a portfolio of clinical solutions spanning both modern, AI-powered capabilities, including generative AI, LLMs, and intelligent automation, and production business applications. Bringing deep, practical experience applying AI across the full development lifecycle, you will leverage AI-powered development assistants to accelerate ideation, design, coding, testing, and troubleshooting.
You will expand your leadership impact by partnering closely with stakeholders, data scientists, and engineers while continuing to work hands-on with systems that deliver measurable improvements in clinical development workflows and decision-making.
Key Responsibilities- Architect, design, and deliver AWS cloud-native solutions across AI/ML capabilities and enterprise business applications.
- Lead the implementation of Generative AI solutions, including retrieval-augmented generation (RAG), agentic workflows, and LLM-integrated systems.
- Drive adoption of AI-augmented development practices, including design acceleration, code generation and review, test automation, and debugging.
- Serve as the primary technical authority for assigned capabilities, making architectural decisions across APIs, data platforms, frontend, infrastructure, and AI tooling.
- Lead technical delivery across onshore and offshore contractor teams, ensuring predictable planning, execution quality, and delivery outcomes.
- Mentor and coach engineers through hands-on guidance, pair programming, code reviews, and knowledge sharing.
- Partner with data science, business, quality, and regulatory stakeholders to align architecture and delivery with program milestones and compliance needs.
- Prototype and validate new capabilities, particularly Generative AI features, to reduce risk before broader team investment.
- Define and execute a technical roadmap aligned with business priorities and R&D Information Systems strategy.
- Oversee production reliability, operational support, and continuous improvement across DevOps and engineering practices.
Basic Qualifications- BA/BS with at least 8 years of experience, MA/MS/MBA with at least 6 years of experience, OR PhD with at least 2 years of experience.
- Strong experience in architecture and system design for scalable, cloud-native applications.
- Demonstrated ability to provide cross-functional technical leadership and own delivery outcomes.
- Practical experience using AI-powered development tools to accelerate design, implementation, and troubleshooting.
- Working knowledge of Generative AI concepts, including LLMs, prompt and context engineering, and agent-based systems.
- Experience with AI orchestration frameworks, such as LangChain, or the ability to ramp up quickly.
- Strong Python development skills, including REST APIs (FastAPI), asynchronous programming, and testing.
- Experience with modern frontend frameworks, such as React, including component architecture and state management.
- Experience with relational and NoSQL databases, including schema design, query development, and performance tuning.
- Strong AWS experience, including ECS or EKS, Lambda, S3, DynamoDB, RDS, and SQS.
- Experience with infrastructure as code (Terraform), CI/CD (GitHub Actions), containers (Docker and Kubernetes), and cloud security fundamentals.
- Proven experience leading contractor or vendor engineering teams while remaining hands-on.
- Ability to communicate technical decisions clearly to both technical and non-technical stakeholders.
Preferred Qualifications- Experience in pharmaceutical or healthcare environments, particularly clinical development.
- Familiarity with GxP, 21 CFR Part 11, and related regulatory frameworks.
- Experience deploying and operating AI or ML solutions in production, including model or LLM evaluation, and monitoring.
The salary range for this position is:
Bay Area: $169,320.00 - $219,120.00.
Raleigh: $146,200.00 - $189,200.00.
Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock-based long-term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company-sponsored medical, dental, vision, and life insurance plans*.
For additional benefits information, visit:
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* Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.
For jobs in the United States:Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment comprised of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status, or other non-job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact for assistance.
For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster.
NOTICE: EMPLOYEE POLYGRAPH PROTECTION ACT
YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT
Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law.
Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team.
Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.
For Current Gilead Employees and Contractors:Please apply via the Internal Career Opportunities portal in Workday.
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