Scientist II

Only local San Francisco Bay Area candidates!

Direct W2 contractors only! No 3rd party agencies! No Visa Sponsorship available.

Client is seeking a qualified and highly motivated individual for the role of Scientist II in
BioSpecimen Acquisition and Management to support Culture Collection and Panel Production activities. The
BioSpecimen Acquisition and Management function at Roche Diagnostic Solutions is a centralized service
organization that supports the acquisition, characterization, and management of biological materials, as well as the
development of select panels for clinical research and the cultivation and characterization of various microorganisms
and mammalian cell lines.
The Scientist II position facilitates daily operations associated with fulfilling service requests for Culture Collection and
panel activities, while providing best-in-class, practical biological solutions to internal customers to drive innovation at client
This position will be based on-site in Pleasanton, California. Specific Responsibilities
Under minimal supervision, execute assigned project activities using established procedures and applying
scientific knowledge and accumulated experience to complete projects involving manipulation of human cell
lines, microorganisms, and/or other biological materials.
Perform standard recombinant DNA techniques, including cloning, restriction digestion, ligation, and
bacterial transformation.
Perform routine and specialized cell culture procedures using adherent and suspension immortalized cell
lines.
Analyze plasmid DNA and RNA transcripts for purity, concentration, and quality.
Make recommendations to resolve problems encountered during experimental procedures.
Receive general direction; plan and execute own work. May act as a project lead.
Maintain an effective scientific knowledge base and apply broad scientific concepts to resolve problems of
moderate scope and complexity.
Analyze alternative approaches to solve problems or develop new perspectives on existing solutions.
Ensure accuracy, quality, and timeliness of all assigned projects, tasks, and related activities. Summarize
experimental results and review conclusions with supervisor or project lead. Communicate results through written reports and presentations as needed.
Maintain accurate electronic records using validated systems, ensuring data is recorded in a timely,
accurate, and consistent manner.
Perform work in accordance with established internal safety guidelines and procedures, and as specified by
applicable external regulatory agencies (e.g., OSHA).
Participate in routine laboratory maintenance, laboratory safety activities, ISO, and QSR implementation. Position Requirements & Experience
Bachelor s degree in Molecular Biology, Cellular Biology, Microbiology, or a related field with 5+ years of
relevant experience, or
Master s degree in Molecular Biology, Cellular Biology, Microbiology, or a related field with 5+ years of
relevant experience.
Experience with aseptic techniques and bacterial and/or mammalian cell culture.
Ability to manually manipulate samples (including plating, pipetting, labeling, and vialing) on a routine basis,
with or without reasonable accommodation.
Experience with cloning techniques, including plasmid design and preparation, restriction enzyme digestion,
ligation, bacterial transformation, and downstream processing.
Experience performing nucleic acid extractions (DNA/RNA), quantification, amplification, and
characterization using tools such as Qubit, Nanodrop, gel electrophoresis, and PCR instruments.
Ability to work in a laboratory environment on a daily basis under BSL-2 laboratory conditions, with or
without reasonable accommodation, including work with infectious or engineered biological materials and a
variety of sample types (e.g., blood, serum, urine, stool).
Ability to work effectively in a dynamic, collaborative team environment with multiple stakeholders across the
organization.
Understanding of good laboratory practices, data integrity, and documentation standards.
Ability to plan work independently and determine next steps within the context of an overall project.
Proficiency with Microsoft Office and Google applications.
Experience with LIMS software, electronic lab notebooks (eLN), and JMP is preferred.
Client-facing experience is a plus. Personal Characteristics & Cultural Fit
Highly organized and detail oriented.
Flexible and adaptable to shifting priorities, unique biological material handling requirements, and evolving
organizational needs.
Strong written and verbal communication skills; ability to follow written and verbal instructions.
Passionate about biorepository management and working within a global, matrixed organization.
Demonstrated aptitude for cross-functional collaboration.
Results- and goals-oriented mindset.