Apply Now

Principal Mechanical Engineer II, Early Research and Development

Santa Clara, CA, US • Posted 9 hours ago • Updated 9 hours ago

Full Time

On-site

USD 79.45 per hour

Fitment

Dice Job Match Score™

📋 Comparing job requirements...

Job Details

Skills

Research and Development
Medical Devices
Pharmaceutics
Testing
Innovation
Motivation
Collaboration
System Integration
Functional Design
Systems Architecture
IT Strategy
Mechanical Engineering
Systems Design
Thermal Management
Sensors
3D CAD
SolidWorks
Manufacturing
Machining
Injection Molding
3D Printing
Computer Hardware
Chemistry
Interfaces
Rapid Prototyping
Python
LabVIEW
Data Acquisition
Mentorship
Control Flow Diagram
Computational Fluid Dynamics
FEA
Next Generation Sequencing
Genomics
Instrumentation
Product Development
Communication
Management

Summary

Senior Mechanical Engineer

A Medical Device Manufacturing / Pharmaceutical client of Sharp Decisions is seeking a Senior Mechanical Engineer in Santa Clara, CA. This is a 6-month contract with possible extension, offering $79.45/hour on a W2.

Job Description

This is a hands-on role for a multidisciplinary expert focused on solving core mechanical challenges for next-generation platforms. The role involves designing, building, and testing innovative electro-mechanical, pneumatic, thermal, and fluidic solutions to ensure system performance, reliability, and longevity.

The Principal Mechanical Engineer will drive innovation for next-generation instrumentation, requiring high motivation, independence, and resourcefulness in a fast-paced, collaborative environment.
Core Responsibilities

Lead end-to-end mechanical design and development of electro-mechanical, pneumatic, fluidic, and thermal sub-systems.
Collaborate with cross-functional engineering teams to define and manage technical interfaces.
Develop mechanisms for automated reagent and flow cell loading, clamping, and sealing.
Design and integrate thermal control systems including heating/cooling elements and sensors.
Partner with simulation teams to validate CFD, thermal, and optical models.
Serve as technical expert during system integration, verification, and troubleshooting.
Lead cross-functional design reviews and resolve technical trade-offs.
Manage timelines and deliverables for mechanical sub-systems.
Create and maintain detailed CAD models, drawings, and specifications.
Contribute to system architecture and technical strategy.
Present technical progress and engineering decisions to stakeholders.

Required Qualifications

PhD with 3+ years, Master's with 4+ years, or Bachelor's with 7+ years of relevant experience.
Hands-on expertise in mechanical, electro-mechanical, and pneumatic system design.
Experience in thermal management and precision temperature control systems.
Experience with fluidics systems (pumps, valves, tubing, sensors).
Proficiency in 3D CAD tools (e.g., SolidWorks).
Experience with manufacturing processes (machining, injection molding, 3D printing).
Strong troubleshooting skills across hardware, software, and chemistry interfaces.
Experience with machine shop tools and rapid prototyping technologies.
Proficiency in Python, LabVIEW, or similar tools for device control and data acquisition.

Preferred Qualifications

Experience leading technical projects and mentoring engineers.
Experience with simulation tools such as CFD and FEA.
Experience with next-generation sequencing (NGS) or genomics instrumentation.
Experience in regulated product development environments.
Strong communication and interpersonal skills.
Ability to manage multiple priorities in a fast-paced environment.2

#LI-NK1

Employers have access to artificial intelligence language tools (“AI”) that help generate and enhance job descriptions and AI may have been used to create this description. The position description has been reviewed for accuracy and Dice believes it to correctly reflect the job opportunity.

Dice Id: sharpdec
Position Id: 52277
Posted 9 hours ago

Create job alert

Never miss an opportunity! Create an alert based on the job you applied for.

Santa Clara, California

•

Today

Title: Principal Mechanical Engineer II, Early Research and Development Description: A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. We are working to make next-generation sequencing simple and accessible enough for routine use. By accelerating clinical research, streamlining workflows, and expand

Easy Apply

Contract

$57.49

Sr. Mechanical Engineer

Milpitas, California

•

Today

Company Overview KLA is a global leader in diversified electronics for the semiconductor manufacturing ecosystem. Virtually every electronic device in the world is produced using our technologies. No laptop, smartphone, wearable device, voice-controlled gadget, flexible screen, VR device or smart car would have made it into your hands without us. KLA invents systems and solutions for the manufacturing of wafers and reticles, integrated circuits, packaging, printed circuit boards and flat panel d

Full-time

USD 117,800.00 - 200,300.00 per year

Staff Mechanical Engineer

Sunnyvale, California

•

Today

Work Schedule First Shift (Days) Environmental Conditions Laboratory Setting, Office, Some degree of PPE (Personal Protective Equipment) required (safety glasses, gowning, gloves, lab coat, ear plugs etc.) Job Description As part of the Thermo Fisher Scientific team, you'll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life every single day to enable our customers to make the world healthier, cleaner and safer. We provi

Full-time

USD 129,400.00 - 176,000.00 per year

Staff Engineer, Mechanical Design

San Jose, California

•

Today

Req ID: 133350 Region: Americas Country: USA State/Province: California City: San Jose Summary Our Engineering Team is seeking a highly motivated and self-driven candidate qualified for the position of Mechanical Engineering to be a part of a market leading Hardware Design Group. The successful candidate will be responsible for mechanical engineering assignments related to hardware products as well as systems including development of new products, updates to existing products or sustaining

Full-time

Search all similar jobs

Principal Mechanical Engineer II, Early Research and Development

Dice Job Match Score™

Job Details

Skills

Summary

Similar Jobs