Platform Infrastructure Engineer

Job Family:
Database Administration (Digital)

Travel Required:
None

Clearance Required:
Ability to Obtain Public Trust

What You Will Do:
We are searching for a Platform Infrastructure Engineer to support future opportunities. The person in this role will install, configure, optimize, and validate scientific platforms and underlying on-premises and cloud-based infrastructure to ensure high availability, security, and performance for biomedical research and laboratory automation. This position will be based in Bethesda, MD.

• Design, implement, and optimize platform infrastructure, including migrating from legacy on-premise solutions to cloud environments (AWS, Azure, Google Cloud Platform) with high reliability and scalability.
• Install and configure high-throughput screening (HTS) platforms, Automated Compound Management Systems, and platform components.
• Set up and maintain networking equipment, cloud platform resources, and high-performance computing (HPC) clusters supporting scientific platforms.
• Perform platform validation, integration testing, and maintain audit-ready documentation, including support for Authority to Operate (ATO) processes.
• Implement and maintain monitoring, backup/restore, and change control processes using tools such as Nagios, Ganglia, XDMoD, and SIEMs.
• Apply industry-standard and NIH-mandated security measures, conduct vulnerability assessments, and ensure compliance with NIST, CIS, and other frameworks.
• Automate deployment workflows using tools like Ansible, Terraform, and Packer.
• Collaborate with vendors, researchers, and internal teams for upgrades, lifecycle management, and solution transitions.
• Lead quarterly patch cycles and coordinate with external stakeholders.
• Support troubleshooting, diagnostics, and technical support for scientific platforms.

What You Will Need:

• Bachelor degree in Engineering, Information Technology, Computer Science, or related field.
• A minimum of TWO (2) years of platform engineering or systems integration experience; experience with cloud services and HPC environments preferred.
• Experience with laboratory automation and regulated change/configuration management.
• Familiarity with scripting (PowerShell, Python, Bash, Ruby) and containerization (Docker, Kubernetes).
• Knowledge of cybersecurity best practices, zero trust architecture, and compliance frameworks (NIST, CIS, ISO 2700 Series).
• Experience with monitoring, ITSM tools (ServiceNow, Remedy), and infrastructure as code.

What Would Be Nice To Have:

• Experience supporting cloud services (AWS EC2, EKS, IAM, S3, RDS, etc.).
• Knowledge of HPC architecture, performance optimization, and scientific workflow support.
• Strong communication, documentation, and multitasking skills.

The annual salary range for this position is $65,000.00-$108,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs.

What We Offer:

Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include:

• Medical, Rx, Dental & Vision Insurance
• Personal and Family Sick Time & Company Paid Holidays
• Parental Leave
• 401(k) Retirement Plan
• Group Term Life and Travel Assistance
• Voluntary Life and AD&D Insurance
• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts
• Transit and Parking Commuter Benefits
• Short-Term & Long-Term Disability
• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities
• Employee Referral Program
• Corporate Sponsored Events & Community Outreach
• Care.com annual membership
• Employee Assistance Program
• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)
• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse

Guidehouse is an Equal Opportunity Employer-Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1- or via email at All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.

All communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.

If any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse's Ethics Hotline. If you want to check the validity of correspondence you have received, please contact Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant's dealings with unauthorized third parties.

Guidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.