Senior principal developer jobs in boston, ma

Remote or Boston, Massachusetts

•

Today

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn m

Full-time

USD 140,000.00 - 241,500.00 per year

Senior Principal Engineer, Silicon Device & Key Product Enablement

Wilmington, Massachusetts

•

Today

About Analog Devices Analog Devices, Inc. (NASDAQ: ADI) is a global semiconductor leader that bridges the physical and digital worlds to enable breakthroughs at the Intelligent Edge. ADI combines analog, digital, AI, and software technologies into solutions that combat climate change, reliably connect humans and the world, and help drive advancements in automation and robotics, mobility, healthcare, energy and data centers. With revenue of more than $11 billion in FY25, ADI ensures today's inno

Full-time

USD 167,090.00 - 241,955.00 per year

Senior Principal Engineer, Late Stage LNP Process Development

Boston, Massachusetts

•

Today

At Lilly, the work is demanding because patients are waiting. We unite caring with discovery to help make life better for people around the world, knowing that every decision, every detail, and every day matters. Headquartered in Indianapolis, Indiana, our over 50,000 employees around the globe take on complex challenges to discover and deliver life-changing medicines, strengthen how health is understood and managed, and support the communities we serve. This is hard, urgent, selfless work-but i

Full-time

USD 110,250.00 - 189,200.00 per year

Principal / Sr. Principal DSP Engineer - Platforming

Framingham, Massachusetts

•

Today

Principal / Sr. Principal DSP Engineer - Platforming Key responsibilities: Lead DSP architecture, implementation, integration, and optimization activities across multiple product platforms. Translate research algorithms and reference implementations into scalable production DSP components. Define implementation approaches, interfaces, performance requirements, and validation strategies. Provide technical leadership and mentoring to DSP engineers working across multiple locations. Resolve comple

Full-time

USD 55.00 - 65.00 per hour

Senior Principal AI/ML Product Engineer- Full Stack

Boston, Massachusetts

•

Today

Optum is a global organization that delivers care, aided by technology to help millions of people live healthier lives. The work you do with our team will directly improve health outcomes by connecting people with the care, pharmacy benefits, data and resources they need to feel their best. Here, you will find a culture guided by inclusion, talented peers, comprehensive benefits and career development opportunities. Come make an impact on the communities we serve as you help us advance health op

Full-time

USD 184,600.00 - 316,500.00 per year

Hardware Senior Principal Engineer ? System Integration

Franklin, Massachusetts

•

Today

Infrastructure Solutions Group (ISG) builds the products that power infrastructure, solutions, and data management our customers need most. Our teams design and develop the hardware and software that connect infrastructure, accelerate computational workloads, integrate across the stack, protect data continuity, and deliver the platforms, applications, and diagnostics our customers rely on every day at enterprise scale.Some product builders follow the rules. Ours rewrite them.Within ISG, innovati

Full-time

Senior / Principal Data Infrastructure Engineer

Cambridge, Massachusetts

•

Today

What if you could join an organization that creates, resources, and builds life sciences companies that invent breakthrough technologies in order to transform health care and sustainability? About Expedition: Expedition Medicines is a privately held, early-stage biotechnology company pioneering the emerging field of Protein Editing. At Expedition Medicines we create small molecules that edit protein structure and function to unlock presently undruggable targets and a broad array of therapeutic

Full-time

USD 165,000.00 - 209,000.00 per year

Senior Principal Embedded Software Engineer

Bedford, Massachusetts

•

Today

At MITRE, your passion fuels work that impacts our nation and improves lives. This is where your skills strengthen national security, cybersecurity, health, transportation, and citizen services. We're a nonprofit engineering, applied research, and advanced technology organization working in the public interest. With objectivity and integrity at our core, we lead federally funded research and development centers for U.S. government agencies - collaborating with industry and academia to deliver in

Full-time

USD 202,000.00 - 252,500.00 per year

Thermal Senior Principal Engineer

Franklin, Massachusetts

•

Today

Job Description Infrastructure Solutions Group (ISG) builds the products that power infrastructure, solutions, and data management our customers need most. Our teams design and develop the hardware and software that connect infrastructure, accelerate computational workloads, integrate across the stack, protect data continuity, and deliver the platforms, applications, and diagnostics our customers rely on every day at enterprise scale. Some product builders follow the rules. Ours rewrite them.

Full-time

USD 164,000.00 - 226,000.00 per year

Mechanical Senior Principal Engineer

Franklin, Massachusetts

•

Today

Full-time

USD 164,000.00 - 226,000.00 per year

Hardware Senior Principal Engineer - System Integration

Franklin, Massachusetts

•

Today

Full-time

USD 176,000.00 - 242,000.00 per year

Electrical Systems Senior Principal Engineer

Hopkinton, Massachusetts

•

Today

Full-time

Mechanical Senior Principal Engineer

Franklin, Massachusetts

•

Today

Full-time

Senior Principal Program Protection Engineer (Embedded Software Engineer)

Tewksbury, Massachusetts

•

Today

Job DescriptionDate Posted: 2026-05-04\nCountry: United States of America\nLocation: US-MA-TEWKSBURY-TB3 ~ 50 Apple Hill Dr ~ CONCORD BLDG, Tewksbury Tb3 300 Concord\nPosition Role Type: Onsite\nU.S. Citizen, U.S. Person, or Immigration Status Requirements: The ability to obtain and maintain a U.S. government issued security clearance is required. U.S. citizenship is required, as only U.S. citizens are eligible for a security clearance\nSecurity Clearance Type: DoD Clearance: Secret\nSecurity

Full-time

Senior Staff Software Engineer, Cloud Services

Waltham, Massachusetts

•

Today

The Boston Dynamics Central Software (CSW) team is seeking a creative and passionate Senior Staff Software Engineer to join our dynamic and collaborative team. If you enjoy learning new technologies and are driven to improve the lives of your team members, this role offers an exciting opportunity to make a significant impact. As a Senior Staff Software Engineer on the Cloud Engineering team, you will be instrumental in developing cloud-based services and solutions that are used across our compa

Full-time

USD 150,000.00 - 190,000.00 per year

Sr. Staff Engineer - Polymer Biomanufacturing

Woburn, Massachusetts

•

Today

We are the people who give possibilities purpose BD is one of the largest global medical technology companies in the world. Advancing the world of health is our Purpose, and it's no small feat. It takes the imagination and passion of all of us-from design and engineering to the manufacturing and marketing of our billions of MedTech products per year-to look at the impossible and find transformative solutions that turn dreams into possibilities. Job Description The Sr. Staff Engineer, Polymer

Full-time

USD 161,400.00 - 258,200.00 per year

Senior Staff Perception Engineer

Waltham, Massachusetts

•

Today

We are seeking a Senior Staff Perception Engineer to join our Stretch PerML (Perception and Machine Learning) team. Our team builds and maintains systems that enable the Stretch robot to intelligently manipulate objects in its warehouse environments. As a Senior Staff Perception Engineer, you will set the technical direction for Stretch's perception stack. You will own key perception pipelines (e.g. object detection, tracking, state estimation) and drive the architecture, development, and mainte

Full-time

USD 150,000.00 - 190,000.00 per year

Senior Staff Firmware Engineer

Waltham, Massachusetts

•

Today

About the Role We are seeking a highly motivated and experienced Senior Staff Firmware Engineer to join the Atlas team at Boston Dynamics. In this role, you will play a critical part in designing, developing, and delivering cutting-edge firmware solutions for advanced humanoid robots. You will be involved in the full firmware development lifecycle, from concept to production, and will have the opportunity to work on challenging projects with a talented team of engineers. Responsibilities: Desi

Full-time

USD 160,000.00 - 200,000.00 per year

Senior Staff Engineer, Modeling and Data Applications

Lexington, Massachusetts

•

Today

By clicking the "Apply" button, I understand that my employment application process with Takeda will commence and that the information I provide in my application will be processed in line with Takeda's Privacy Notice and Terms of Use. I further attest that all information I submit in my employment application is true to the best of my knowledge. Job Description Senior Staff Engineer, Modeling Are you looking for a patient-focused company that will inspire you and support your career? If so, b

Full-time

USD 137,000.00 - 215,270.00 per year

Sr Staff Engineer Software

Boston, Massachusetts

•

Today

Our Mission At Palo Alto Networks , we're united by a shared mission-to protect our digital way of life. We thrive at the intersection of innovation and impact, solving real-world problems with cutting-edge technology and bold thinking. Here, everyone has a voice, and every idea counts. If you're ready to do the most meaningful work of your career alongside people who are just as passionate as you are, you're in the right place. Who We Are In order to be the cybersecurity partner of choice, w

Full-time

USD 126,000.00 - 204,500.00 per year

Senior principal developer jobs in Boston, MA, USA