Sr. IT Program Manager

Work Schedule
Standard (Mon-Fri)

Environmental Conditions
Office

Job Description

Uncover a remarkable opportunity at Thermo Fisher Scientific Inc. to push global advancements in health, cleanliness, and safety as a Sr. IT Program Manager in Waltham. Become a part of our elite team, guiding ambitious IT projects that enhance quality, compliance, and supply chain operations within our Contract Development and Manufacturing Organization (CDMO).

Argument Development & Case Creation

• Collaborate with business leaders to determine opportunities where technology provides measurable business value.
• Develop and present cases justifying investments by outlining the value, benefits, and resource requirements.
• Translate strategic goals into actionable IT roadmaps that support growth, scalability, and regulatory compliance.
• Support portfolio governance and prioritization discussions through data-driven analysis.

Financial Oversight

• Manage program budgets, forecasts, and capital/operating expense planning.
• Monitor and report financial performance, ensuring accountability and transparency.
• Identify cost optimization and efficiency opportunities within vendor and system portfolios.
• Provide variance analysis and investment recommendations to senior leadership.

Vendor & Partner Management

• Lead the selection, contracting, and performance oversight of technology vendors and service providers.
• Negotiate statements of work (SOWs) and service-level agreements (SLAs) in collaboration with Procurement and Legal.
• Monitor vendor delivery, quality, and compliance performance against expectations.
• Champion positive relationships that drive innovation and operational excellence.

Quality, Compliance & Inspection Readiness

• Ensure all IT programs meet global regulatory and validation standards (21 CFR Part 11, GxP, GAMP 5, EU Annex 11).
• Maintain ongoing inspection readiness by ensuring complete validation documentation and traceability.
• Partner with Quality and Compliance teams to prepare for internal and external audits.
• Represent IT during inspections and drive timely remediation where vital.

Systems & Integration

• Manage the incorporation and enhancement of essential platforms like ERP, MES, QMS, LIMS, and SCM systems.
• Ensure system development aligns with data integrity, cybersecurity, and infrastructure standards.
• Collaborate with architects and functional leaders to enable process harmonization and scalability.

Experience

• 5+ years of proven experience leading IT projects within the life sciences, biotech, or pharmaceutical manufacturing industry (Preference for CDMO experience).
• Demonstrated success leading large, complex, cross-functional technology initiatives.
• Strong understanding of Quality, Regulatory, and Supply Chain business procedures.
• Experience developing and leading program budgets and justifications.
• Proven success leading vendors and third-party service providers.
• Practical familiarity with ERP, MES, QMS, LIMS, or Supply Chain systems.
• Solid understanding of GxP and data integrity requirements.
• Strong leadership, influencing, and collaboration skills.
• Excellent communication and presentation abilities with executive audiences.
• Ability to lead multiple initiatives in a fast-paced, regulated environment.
• Certifications such as PMP, ITIL, or Agile Scrum Master preferred.